Clinical Trial Navigator

Model: x-ai/grok-4.1-fast

Status: Completed

Cost: $0.089

Tokens: 247,597

Started: 2026-01-05 14:35

Section 05: User Research & Validation Plan

1 Key Assumptions to Validate

Prioritize high-risk assumptions. Target 20-30 interviews and 300+ survey responses across patients (70%) and caregivers (30%).

Category & Assumption	Risk	Validation Method	Target Evidence
Problem Assumptions
Patients with chronic conditions search for trials ≥1x/quarter but abandon due to overwhelming search results (450k+ trials).	High	Interviews + surveys	70%+ confirm frequency & frustration
Eligibility criteria jargon prevents 80%+ of patients from self-assessing fit.	High	Observation + think-aloud tests	80%+ rate incomprehensibility >7/10
Patients miss trials due to lack of awareness for their specific condition.	High	Interviews	60%+ unaware of relevant trials
No reliable tracking/notifications lead to repeated searches (avg. 2-3 hrs/week).	Medium	Surveys	50%+ spend >2hrs/week re-searching
Geographic/logistical barriers deter 70%+ from applying.	Medium	Interviews	Quotes on travel/cost barriers
Caregivers face amplified emotional burden in research.	Medium	Interviews	50%+ of caregivers rate pain 8+/10
ClinicalTrials.gov UX drives 90%+ abandonment.	Medium	Competitive tasks + surveys	85%+ dissatisfaction score
Solution Assumptions
Patients will share health data via questionnaire/FHIR for matching.	High	Prototype input tests	70%+ complete questionnaire
AI plain-language summaries achieve 85%+ trust/accuracy rating.	Critical	Blind A/B tests vs. original text	85%+ prefer AI version
Match scores + explanations drive trial applications.	Medium	Clickable prototype	60%+ click "Apply" on >70% matches
Notifications increase engagement 3x vs. manual checks.	Medium	Wizard of Oz notifications	3x open rate
Logistics helper reduces perceived barriers by 50%.	Medium	Before/after surveys	50%+ barrier score drop
Comparison views aid decision-making for 80%+ users.	Low	Usability tests	80%+ find helpful
Business Assumptions
Patients/caregivers pay $9.99/mo for premium features.	Critical	Van Westendorp + pre-orders	60%+ accept $9.99
Freemium converts at 10%+ to premium.	High	Fake door tests	10%+ upgrade clicks
CAC < $20 via patient communities/SEO.	High	Ad experiments	<$20 proven
B2B leads viable at $50/qualified patient.	High	Hospital outreach surveys	20%+ interest from 50 contacts
LTV >3x CAC within 12 months.	Low	Cohort projections	Modeled LTV $60+

2 Customer Discovery Interview Guide (60-90 min)

Target: 25 interviews (18 patients, 7 caregivers). Recruit via Reddit (r/cancer, r/rarediseases), patient Facebook groups, LinkedIn. Incentive: $50 Amazon card. Record w/ Otter.ai.

Part 1: Background (10 min)
- Tell me about your condition and treatment journey.
- How long seeking alternatives to standard care?
- Role as patient/caregiver?

Part 2: Problem (20 min)
- Walk me through last trial search.
- How often? Triggers? Time spent?
- Worst frustrations (jargon, volume, logistics)?
- Emotional impact?
- Missed opportunities?

Part 3: Current Solutions (15 min)
- Tools used (ClinicalTrials.gov, Antidote)? Likes/dislikes?
- Switched? Why?
- Switch triggers?

Part 4: Solution (15 min)
- Tool matching trials via questionnaire, plain-language summaries, trackers, logistics help?
- Valuable features? Concerns (accuracy, privacy)?
- Trial price: $9.99/mo?
- Approvers?

Part 5: Wrap-up (10 min)
- Pain scale 1-10?
- Beta interest?
- Referrals?

3 Survey Designs

Use Typeform/Google Forms. Distribute via patient forums, Twitter. Target 300+ responses.

Screening Survey (7 questions)

1. Condition? (Cancer/Rare disease/Autoimmune/Other)
2. Searched trials last 6 mo? (Yes/No)
3. Primary frustration? (Jargon/Search volume/Logistics/Other)
4. Pain scale 1-10?
5. Tools used?
6. Time spent/mo?
7. Interview interest? ($50 card)

Validation Survey (18 questions)

- Problem frequency/satisfaction (NPS on tools).
- A/B messaging: "Match trials to your health" vs. "Simplify trial eligibility."
- Van Westendorp pricing: Too cheap/expensive/expected/indifferent for $9.99/mo.
- Demographics: Age, condition stage.

4 Landing Page & Prototype Experiments

Build on Carrd/Webflow. Ads: Facebook (patient groups), Google ("clinical trials [condition]"). Budget: $750.

A/B Headlines:

"Discover matching clinical trials in minutes – no jargon."
"AI matches trials to your condition + tracks changes."
"Overcome trial barriers: eligibility, location, logistics."

Metrics: >1k visitors, >7% signup (70+ emails), <8% bounce.

Prototype Options (Recommended: Wizard of Oz):

Option	Cost	Timeline	Best For
Wizard of Oz (manual AI outputs)	$0 + time	2-4w	Deep learning, WTP
Concierge MVP (10 users)	$0 + time	4-6w	Feature prioritization
Clickable Figma	$300	1-2w	UX flows

Fake Door/Pre-Order: Show premium tiers; >12% clicks, >3% pre-orders ($9.99 early bird, refundable).

5 8-Week Validation Timeline

W1-2: Problem

15 interviews, 200 screening surveys, pattern analysis

W3-4: Solution

Landing A/B ($500 ads), 100 waitlist, 20 follow-up surveys

W5-6: WTP

10 pricing interviews, fake door, 5-10 pre-orders

W7-8: Prototype

Wizard Oz for 15 users, NPS/feedback, iterate

6 Go/No-Go Criteria & Synthesis Template

Metric	Target	Actual	Pass?
Problem validation (interviews)	70%+ pain 8+/10
Landing signup	>7%
Price acceptance	60%+ $9.99
Pre-orders	10+
Prototype NPS	>50

Synthesis Template:

Problem: Top pains/quotes/unexpected.
Solution: Valued features/ignores/UX.
Pricing: Optimal point/sensitivity.
GTM: Channels/objections.

Next Steps: Launch Week 1 tasks immediately. Pivot if <4/5 criteria pass.